What SisEmbrio publicly reports about Brazilian IVF activity—and what it does not.

If you are comparing IVF destinations, you may see Brazilian “national fertility data” quoted online. The official public system behind much of that conversation is SisEmbrio (Sistema Nacional de Produção de Embriões), maintained by ANVISA (Agência Nacional de Vigilância Sanitária).

SisEmbrio answers a sanitary and production question: how much assisted-reproduction activity reporting centers submit—cycles, cryopreservation volumes and related laboratory activity fields. It does not publish patient-specific live-birth success rates you can treat as a clinic ranking or as a substitute for Understanding outcomes.

That distinction already appears on our IVF regulation in Brazil and Why Brazil pages. This report expands it with verified open-data figures and source links.

ANVISA RDC nº 29, of 12 May 2008, instituted SisEmbrio and approved technical rules for national registration of Bancos de Células e Tecidos Germinativos (BCTG) and for sending information on human embryos produced by IVF techniques and not used in the respective procedure. ANVISA creates and maintains the system; each BCTG is responsible for filling and updating it.

Under that resolution, participating banks update SisEmbrio annually, with a filing deadline of 31 January for the previous calendar year’s data. The Brazilian government’s service page for SisEmbrio registration describes an electronic cadastro of Centro de Reprodução Humana Assistida (CRHA) / BCTG so centers can submit annual quantitative production data on cells, germinal tissues and embryos to ANVISA.

ANVISA’s public SisEmbrio page identifies the system simply as Sistema Nacional de Produção de Embriões. Open-data documentation on dados.gov.br explains that SisEmbrio compiles information from assisted-reproduction centers and makes it available to the public, to establishments, and to state, municipal and Federal District sanitary surveillance bodies that license and inspect locally.

Related sanitary instruments cited on the gov.br service page include RDC nº 23/2011 (BCTG technical regulation and updates), RDC nº 214/2018 (good practices in cells), and Lei nº 11.105/2005 (Biosafety Law). Medical ethics for physicians sit in a separate layer—CFM Resolution 2,320/2022—covered on our regulation page.

ANVISA publishes SisEmbrio-derived open data on dados.anvisa.gov.br. Two CSV files are listed: an older balanço series (2008–2019) and a procedimento series from 2020 onward—`DADOS_ABERTOS_PROCEDIMENTO_CELULA_EMBRIAO.csv`. The Portal de Dados Abertos dataset page points to those same filenames.

We downloaded the 2020-onward CSV on 30 September 2026 (America/Sao_Paulo). The file’s HTTP Last-Modified header was 30 September 2026, 05:39 GMT. It contains 1,137 data rows across reference years 2020–2025, with one row per reporting unit in a city (for example, 2025 includes 201 rows; São Paulo city alone has 33 rows).

Activity-oriented fields used on this page include IVF cycles by age band (`QT_CICLOS_REALIZADOS_FIV_MENOR_35` and `QT_CICLOS_REALIZADOS_FIV_35_MAIS`), embryos frozen in an IVF context (`QT_EMBRIOES_CONGELADOS_FIV_*`), oocyte-retrieval cycle counts, egg-freezing cycles and oocytes cryopreserved, plus region (`DS_REGIAO`).

The same file also contains pregnancy counts and rate-like fields (fertilization and gestation indicators). Those are not live-birth rates. Consistent with our regulation framing, we do not republish them here as marketing success rates or as internationally comparable clinic outcomes.

The table below sums the official open-data columns named above across all reporting rows for each reference year. These are activity volumes, not live-birth rates. English labels are explanatory translations of the Portuguese field names.

In 2025, the file shows 44,366 IVF cycles (sum of FIV cycles in women under 35 and women 35+), of which 74.1% were in the 35+ band; 144,548 embryos frozen in an IVF context; 18,631 egg-freezing cycles; and 147,062 oocytes cryopreserved. The same year contains 201 reporting rows.

Embryos frozen in an IVF context rose from 86,833 in 2020 to 144,548 in 2025 (about +66.5% over that interval in this file). IVF-cycle totals in the same file moved from 33,714 (2020) to 44,366 (2025), with year-to-year variation—not a single smooth curve.

Regional concentration remains strong. In 2025, the Southeast accounted for about 63.9% of summed IVF cycles in the file, followed by the South (14.5%), Northeast (10.8%), Central-West (7.9%) and North (1.3%), with a small share of rows lacking a region label.

Source under the table: ANVISA open data file `DADOS_ABERTOS_PROCEDIMENTO_CELULA_EMBRIAO.csv` (SisEmbrio-derived), years 2020–2025, downloaded 30 September 2026. We omit press totals that we could not reproduce from this file.

SisEmbrio activity figures are not patient-specific live-birth rates. They should not be quoted as marketing success rates for an individual patient, as a clinic league table, or as a simple international “success” comparison.

Even when a national dataset includes pregnancy or fertilization indicators, those endpoints are not the same as live birth per retrieval or per transfer for a defined age and diagnosis group. Denominators, inclusion rules and follow-up differ. A national activity total cannot tell you what will happen in your cycle.

Brazil Fertility does not claim SisEmbrio rankings for ENNE or Nilo Frantz Medicina Reprodutiva. We found no official public SisEmbrio ranking that places those clinics in a success-rate order—and we will not invent one.

For how this site discusses results language, read Understanding outcomes. For the sanitary and ethical framework around reporting, read IVF regulation in Brazil.

• Activity / production volume ≠ live birth.
• National or regional totals ≠ your personal prognosis.
• Pregnancy or fertilization fields in open data ≠ live-birth marketing rates.
• No invented clinic rankings from SisEmbrio on this site.

Use SisEmbrio open data to understand scale and structure: Brazil has a large, regionally concentrated assisted-reproduction activity footprint, with a high share of IVF cycles reported in women aged 35 and over in the 2025 file.

Do not use those totals to pick a clinic, to compare Brazil against CDC/SART-style live-birth tables as if they were the same product, or to skip a conversation about denominators with your physician.

Useful questions: What is being counted—cycles, embryos frozen, pregnancies or live births? Which patients are included? Is the figure national activity or a clinic’s own audited series? How does CFM consent guidance ask the unit to explain results for the technique proposed?

Travel and pathway pages on this site (IVF in Brazil, how long to stay, costs orientation) address logistics separately. Regulation and activity reporting do not replace a personal clinical plan.

Brazil Fertility coordinates an international program with treating care at ENNE (São Paulo) and Nilo Frantz Medicina Reprodutiva (Porto Alegre)—clinics of Grupo Nilo Frantz. Brazil Fertility itself is not a treating clinic and does not claim separate laboratory accreditation beyond disclosing those providers.

We talk about ANVISA sanitary expectations, CFM ethical rules and SisEmbrio activity reporting so patients can ask better questions—not so a national CSV can be mistaken for a promise of pregnancy.

When ANVISA’s consolidated PDF report library is available, readers should prefer primary gov.br documents. At the time this page was prepared (30 September 2026), the SisEmbrio reports publication page on gov.br/anvisa was showing a maintenance message; the open-data CSV remained the verifiable numeric source we could fetch and sum.

If you want help reading how regulation and pathway choice fit your situation, begin a conversation. Clinical decisions remain with the identified physician and clinic.

These answers match the FAQ schema on this page and the sources cited above.

• What is SisEmbrio? — ANVISA’s Sistema Nacional de Produção de Embriões: national reporting of assisted-reproduction production/activity by registered CRHA/BCTG centers.
• Does SisEmbrio publish live-birth success rates? — No. Treat public SisEmbrio figures as activity/production reporting, not patient-specific live-birth marketing rates.
• What is the latest year in the open-data file we used? — Reference year 2025 in DADOS_ABERTOS_PROCEDIMENTO_CELULA_EMBRIAO.csv (file fetched 30 September 2026).
• Can I use SisEmbrio to rank ENNE or Nilo Frantz? — We do not claim official SisEmbrio clinic rankings for partner clinics; none were verified in public sources for that purpose.
• Where should I go next? — IVF regulation in Brazil for the legal/ethical frame; Understanding outcomes for result language; Contact to begin with the international program.